Cosmelan® De-Pigmentation Program

The cosmelan® method consists of 4-phases which are necessary to achieve the target outcome. Intense depigmentation in cabin in phase 1 and treatment for home use in phases 2, 3 and 4.

Its online sale is not allowed and must be applied in aesthetic consultation. 

The synergistic action of all the method products ensures: higher depigmenting efficacy, greater comfort during treatment and lower risk of repigmentation.


- corrective action: it removes the deposits of melanin, a pigment that gives colour to the spot in the outermost skin layers

- regulating action: it acts directly in the melanocyte, a cell where melanin is produced, to control its production and keep hyperpigmentation under control


Over 1 million patients. A long track record guarantees the efficacy of cosmelan® method.

Thousands of professionals treat hyperpigmentations with cosmelan® method and recommend it to their patients.

It treats the problem from its origin, removing spots and preventing their reappearance.

is effective against all types of spots of melanin origin, all types of skins and ethnicities.


1. Intense depigmentation

In the salon with removal at home

8 to 12 hours

Following a deep cleansing with the oil-removing solution, cosmelan 1 has a powerful depigmenting effect due to its high concentration of active ingredients. The product should be applied by the professional, who will establish the application time in each case. After the recommended application time, the patient should remove the product at home, completing the first phase.

Instructions for use: apply the 10 g of the cosmelan mask and allow it to act using your professional judgment for 8-12 hours according to the indications on the above technical table for the pack.

Removal of the mask at home: rinse carefully with plenty of lukewarm water, multiple times if necessary, avoiding direct contact with the eyes. In case of erythema, tightness or a sensation of dryness, we recommend applying a layer of melan recovery, allowing it to act for 10-15 minutes.

2. Continuous depigmentation

At home

Month 1

48 hours after removing the cosmelan 1 mask, it is necessary to continue with the daily depigmentation routine to supplement the corrective action of the method and to regulate overproduction of melanin inside the melanocyte.

Instructions for use: apply cosmelan 2 three times a day (morning, midday and night), followed by melan recovery and melan 130 after daytime applications.


In the case of extreme sensitivity during this phase, consider spacing out the applications of cosmelan 2, without abandoning the treatment altogether.

3. Control of hyperpigmentation

At home

Months 2 and 3

At this point, it is important to treat the root cause of the blemish by regulating overproduction of melanin through constant regulation of the melanocyte. This controls both intra- and intercellular melanin production and prevents repigmentation.


Instructions for use: apply cosmelan 2 morning and night, followed by melan recovery, and melan 130 during the day. In case of sun exposure, reapply UV protection at midday.

4. Controlling reappearance

At home

Month 4 to 7

The tendency to develop dark spots represents an ongoing risk. During the control phase, the treatment prevents the reappearance of the treated spots and the formation of new ones, for a longer-lasting result.


Once the method is complete, we strongly recommend continuous use of sun protection as a permanent cosmetic treatment.


Instructions for use: apply cosmelan 2 at night, followed by melan recovery. During the day, apply melan 130 and reapply in cases of direct sun exposure.